DIM, or diindolylmethane, provides protective effects with regards to supporting healthy estrogen metabolism. Combines protective benefits of indole-3-carbinol, diindolylmethane, and other indoles. Dietary indole compounds exert a strong protective effect on tissues such as breast, cervix, and prostate that are most susceptible to the effects of undesirable estrogen metabolites, such as 16-alpha-hydroxyestrone. Indole compounds favorably influence steroid hormone metabolism and help rebalance estrogen in favor of 2-hydroxyestrone, a protective estrogen metabolite.